All of the above advantages are beneficial to aerobic exercise in patients with osteoarthritis, especially in patients with cardiovascular disease and hypertension, thus promoting the recovery of patients. Moreover, LBPP can promote venous return during walking, which significantly reduces heart rate. The force is evenly distributed in the lower part of the human body, and the subject has no sense of pressure. Compared with the suspension weight-reduction system (with a harness to lift the patient on a treadmill and the central part forms a concentrated pressure point), AlterG's advantages are mainly reflected in the patient's comfort during the weight loss process (with the air pressure increased by inflation and the resulting support). ![]() ![]() The AlterG provides body weight support of up to 80% in 1% increments, allowing for a systematically graded exercise program modified to the specific needs of the client (Fig. To overcome these issues, the anti-gravity treadmill (AlterG), as a representative method of Lower body positive pressure (LBPP) treadmills, has been recently proposed as a therapy for patients with osteoarticular diseases and could provide an alternative method for body weight-supported training (BWSTT) by providing a positive pressure chamber that surrounds the individual's lower body and the treadmill. However, clinical application of such therapy is difficult in patients with advanced KOA because of loading exacerbates joint pain, preventing intervention. Therefore, appropriate exercise therapy, such as aerobic exercise, has been known as an effective countermeasure. ![]() The management of KOA based on the Evidence-Based Guidelines involves exercises and strength training and weight control. Due to the above changes, daily life activities are affected accordingly. Continued disease progression leads to gradual impairment of knee function and causes corresponding pain and decreased muscle strength, which associated with maintaining knee stability, resulting in decreased exercise and increased body mass index (BMI), further aggravating knee joint burden and damage. Knee Osteoarthritis (KOA) is a disease characterized by degenerative changes and destruction of articular cartilage.
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